By Philip W. Harvey,David J. Everett,Christopher J. Springall
Despite being considered as the commonest toxicological goal within the endocrine procedure, the adrenal gland has frequently been missed in regulatory trying out. Adrenal Toxicology addresses the elevated curiosity in adrenocortical toxicology and the necessity for a source that makes concepts on hand to check adrenal endocrine disruption.
Examining present suggestions and the most recent developments, Adrenal Toxicology experiences the endocrinology, pharmacology, pathology and toxicology of the adrenal gland. this article presents details at the variety of substances and chemical compounds that have an effect on adrenocortical functionality and indicates standardized ways for in vivo and in vitro evaluation. This quantity additionally offers fresh advancements within the molecular mechanisms of toxicity to the adrenal cortex and medulla, and considers environmental adrenal endocrine disruption in sentinel species.
- reflects the most important advancements remodeled the previous decade
- focuses at the most up-to-date study options, together with their makes use of and limitations
- provides an built-in procedure for adrenal toxicology evaluation
- identifies wisdom and information gaps, delivering impetus for regulatory consideration
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